CAPMUL® GDO
Versatile, high-purity glycerol dioleate for use as a functional lipid excipient in a variety of applications and dosage forms, including liquid-crystal formulation and lipid nanoparticles (LNPs).
Key Benefits of CAPMUL GDO
CAPMUL GDO forms liquid crystal nanostructures in aqueous environments and effectively encapsulates active pharmaceutical ingredients to increase solubility and potentially increase active stability.
- Effective in a multitude of dosage forms.
- Self-assembly characteristics make it an ideal compositional lipid for LNPs.
- Biocompatible and biodegradable, minimizing toxicity concerns, to make it suitable for a wide variety of therapeutic applications.
- Manufactured under cGMP in state-of-the-art manufacturing facility
Increase solubility and stability across a range of dosage forms
Per-Oral
Use as a solubilizer and emulsifier in oral dosage forms like tablets and capsules. It can be used alone or combined with other lipid-based excipients in Self-Emulsifying Drug Delivery Systems (SEDDS) to help improve the solubility of active ingredients and enhance their bioavailability.
Depot and Sustained Release Injections
In phase-forming formulations, CAPMUL GDO can be used to generate liquid-crystal depots. These depots allow for the prolonged release of actives making them ideal for sustained-release injectable formulations.
Topical
CAPMUL GDO increases active solubility in both on-skin and transdermal therapies while improving the skin feel and spreadability of topical creams and gels. In addition it will act as an emulsifier and enhance penetration in transdermal dosage forms.
Ocular
The ability of CAPMUL GDO to self-assemble in various nanostructures, such as micelles, means it can enhance drug stability, protect against degradation, and control the release profile of actives in the eye. Good biocompatability and a low toxicity profile also make CAPMUL GDO suitable for sensitive ocular tissue.
Bioadhesive
The amphiphilic nature and gelling characteristics of CAPMUL GDO make it ideal for bioadhesive formulations which are administered on mucous membranes, such as oral, nasal, ocular, and vaginal dosage forms. CAPMUL GDO enhances drug adhesion which can improve the therapeutic efficacy of actives that would otherwise be rapidly cleared.
Select the right grade of CAPMUL GDO for your formulation
| Product | Characteristics | Dosage Forms |
| CAPMUL® GDO-TX | For non-sterile dosage forms | Per-oral and topical |
| CAPMUL® GDO-CN | High-purity grade for sterile dosage forms | Injectable, pulmonary and ocular |
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Why Choose ABITEC for Functional Lipid Excipients?
- ABITEC are experts in lipid technologies and they will help you to find the right excipient and solve any formulation challenges.
- We have been producing and supplying high-quality ingredients to the pharmaceutical industry for over 50 years
- We are committed to providing safe, effective and reliable products with rigorous quality control and customer service you can trust.
- Our high-quality monograph compliant lipid excipients are manufactured at state-of-the-art manufacturing facilities to comply with strict cGMP and applicable IPEC guidelines.
Legal Disclaimer
CAPMUL® is a trademark of ABITEC Corporation. All information and statements given on this website are believed to be accurate at the time of publication. However, neither ABITEC Corporation nor any of their affiliates make any representations or warranty with respect thereto, including, but not limited to, any results obtained in the processing of the products by customers or any third party. All information and statements are intended for persons having the required skill and know-how and do not relieve the customer or user from verifying the suitability of information and statements given for a specific purpose prior to use of the products. It is entirely the obligation of the customer or user to comply with applicable laws and regulations, and also with all patent or other intellectual property rights of third parties. ABITEC CORPORATION EXPRESSELY DISCLAIMS ANY REPRESENTATIONS OR WARRANTIES OF ANY KIND, WHETHER EXPRESSED OR IMPLIED, AS TO THE ACCURACY, CURRENCY, COMPLETENESS AND/OR THE MERCHANTABILITY OR FITNESS OF A PARTICULAR PURPOSE OF ANY INFORMATION CONTAINED ON THIS WEBSITE AND/OR PRODUCT DESCRIBED OR PROMOTED ON THIS WEBSITE, INCLUDING WARRANTIES WITH RESPECT TO INFRINGEMENT OF ANY PATENT, COPYRIGHT, OR OTHER RIGHTS OF A THIRD PARTY. We reserve the right to change product specifications and specified properties of the products without prior notice.